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Discover the key clinical data in AAV

Our current understanding of patient outcomes in ANCA-associated vasculitis (AAV) is rapidly evolving as more studies are being conducted.

Read the key clinical research papers to find out more about the outcomes in AAV.

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AAV mechanism of disease

See how the interaction between neutrophils and the alternative complement system are at the heart of the vasculitis process in AAV.

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Introduction to AAV

Introduction to AAV

AAV is a rare, severe small vessel vasculitis that affects multiple organs and has a high acute mortality risk1

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Disease Mechanism

Disease Mechanism

The interaction between the activated alternative complement pathway, neutrophils and C5a is at the heart of vasculitic damage in AAV2

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AAV treatment

AAV treatment

A framework of practice for the treatment and management of AAV patients

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References & footnotes
EUVAS

European Vasculitis Society website

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ASN

American Society of Nephrology

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ACR

American College of Rheumatology

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ERA

European Renal Association

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EULAR

European Alliance of Associations for Rheumatology

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KDIGO

Kidney Disease Improving Global Outcomes

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KDIGO recommendations

KDIGO recommendations for the management of individuals with glomerular diseases

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Patient videos and quality of life
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Vasculitis International

Europe

www.vasculitisint.com
Selbsthilfe Vaskulitis e.V.

Germany

www.vasculitisint.com/vpag/vaskulitis-e-v/
Associazione Pazienti della Sindrome di Churg Strauss

Italy

www.apacs-egpa.org
Suomen Vaskuliittiyhdistys ry

Finland

www.vaskuliittiyhdistys.fi
Selbsthilfe Vaskulitis Mainz

Germany

vaskulitis-mainz@gmx.de
Vasculitis Stichting

Netherlands

www.vasculitis.nl
Liga Portuguesa Contra as Doencas Reumaticas

Portugal

www.lpcdr.org.pt
Association Vascularites

France/Belgium

www.association-vascularites.org

Ireland

Asociación Española de Vasculitis Sistémicas

Spain

www.sid-inico.usal.es

United Kingdom

Associazione Malattie Autoimmuni

Italy

www.associazionemalattieautoimmuni.it
Associazione Nazionale Malati Reumatici ONLUS

Italy

www.anmar-italia.it
Australia and New Zealand Vasculitis Society

Australia / New Zealand

www.anzvasculitis.org
Federación Española de Enfermedades Raras

Spain

www.enfermedades-raras.org
Liga Reumatológica Española

Spain

lire.es/
Vasculitis Stowarzyszenie Chorych

Poland

vasculitis.org.pl/